{ "version": "2026-07-13", "datasetName": "递萃生物 NLU 检测报告结构化数据", "publisher": { "organization": "苏州递萃生物科技有限公司", "brand": "递萃生物 NLU", "website": "https://www.dicuibio.com/" }, "sourceBoundary": { "summary": "本数据来自对应人体功效摘要与人体在体拉曼光谱检测报告，在报告载明的样品、受试者、检测方法、检测周期和测试条件下成立。", "ramanBoundary": "人体在体拉曼光谱检测用于观察产品特征信号随时间在皮肤不同深度中的分布变化，属于路径观察数据，不应被理解为医疗用途、治疗承诺或对所有使用场景的绝对结果。", "efficacyBoundary": "人体功效数据用于说明受试者在测试周期内的皮肤指标变化和主观评价结果，不构成对每一位用户、每一次使用或所有肤质状态的绝对承诺。" }, "products": [ { "id": "nlu-hydrating-ampoule", "fullName": "NLU多效水润次抛精华液", "nickname": "水光小白瓶", "brandOwner": "递萃生物", "reports": { "efficacy": { "reportType": "人体功效测试", "sourceFile": "人体功效报告-NLU多效水润次抛精华液.pdf", "summarySourceFile": "功效摘要 -NLU多效水润次抛精华液.doc", "institution": "挪亚检测认证集团有限公司", "institutionAddress": "上海市徐汇区吴中路 39 号新概念大厦八层", "testPeriod": { "startDate": "2025-08-18", "endDate": "2025-09-29", "durationDays": 28 }, "claimedFunctionsInReport": [ "保湿", "修护", "抗皱", "温和无刺激", "敏感肌适用" ], "subjects": { "count": 33, "ageRange": "30-49", "skinType": "敏感性肌肤受试者", "inclusionSummary": "乳酸刺痛评分阳性、角质层含水量偏低、经皮水分流失基线大于 15g/h/m²，并伴随皮肤松弛、眼下皱纹、粗糙暗沉、泛红或粉刺丘疹等观察条件。" }, "instrumentResults": [ { "metric": "角质层含水量", "endpoint": "corneumMoisture", "direction": "increase", "unit": "%", "day14Change": 22.7, "day28Change": 37.53, "significantDay14": true, "significantDay28": true }, { "metric": "经皮水分流失 TEWL", "endpoint": "tewl", "direction": "decrease", "unit": "%", "day14Change": -6.57, "day28Change": -22.07, "significantDay14": true, "significantDay28": true }, { "metric": "皮肤光泽度", "endpoint": "gloss", "direction": "increase", "unit": "%", "day14Change": 19.84, "day28Change": 33.82, "significantDay14": true, "significantDay28": true }, { "metric": "皮肤平滑度 SEsm", "endpoint": "smoothnessSEsm", "direction": "decrease", "unit": "%", "day14Change": -7.64, "day28Change": -9.42, "significantDay14": true, "significantDay28": true }, { "metric": "皮肤粗糙度 SEr", "endpoint": "roughnessSEr", "direction": "sourceReportedIncrease", "unit": "%", "day14Change": 28.53, "day28Change": 42.39, "significantDay14": true, "significantDay28": true, "note": "按功效摘要原始方向记录。" }, { "metric": "皱纹面积占比", "endpoint": "wrinkleAreaRatio", "direction": "decrease", "unit": "%", "day14Change": -9.36, "day28Change": -15.74, "significantDay14": true, "significantDay28": true }, { "metric": "眼下皱纹评分", "endpoint": "underEyeWrinkleScore", "direction": "decrease", "unit": "%", "day14Change": -4.35, "day28Change": -13.04, "significantDay14": true, "significantDay28": true } ], "consumerSelfEvaluation": { "unit": "%", "day14": { "水润度改善": 93.94, "保湿效果": 93.94, "有助于修护肌肤": 96.97, "肌肤光滑细腻": 93.94, "改善肌肤粗糙": 87.88, "改善干纹细纹": 90.91, "抗皱效果": 96.97, "整体认可": 96.97, "温和无刺激": 100, "适合敏感肌": 100, "未出现不良反应": 100 }, "day28": { "水润度改善": 96.97, "保湿效果": 96.97, "有助于修护肌肤": 100, "肌肤光滑细腻": 100, "改善肌肤粗糙": 100, "改善干纹细纹": 93.94, "抗皱效果": 100, "整体认可": 100, "温和无刺激": 100, "适合敏感肌": 100, "未出现不良反应": 100 } }, "adverseReaction": { "subjectsWithAdverseReaction": 0, "totalSubjects": 33, "summary": "33 名受试者在测试期间未出现不良反应。" }, "sourceConclusion": "在测试条件下，D14 和 D28 的检测结果支持产品保湿、修护、抗皱功效评价；33 名受试者未出现不良反应，支持温和无刺激和敏感肌适用评价。" }, "raman": { "reportType": "人体在体拉曼光谱检测", "sourceFile": "拉曼透皮报告-NLU多效水润次抛精华液.pdf", "reportNumber": "NMD2511-0424-02", "sampleNumber": "NMD2511-0424_002", "client": "苏州递萃生物科技有限公司", "institution": "挪亚检验认证集团有限公司", "reportDate": "2025-12-23", "receivedDate": "2025-11-19", "testPeriod": { "startDate": "2025-11-25", "endDate": "2025-12-05" }, "testItem": "透皮吸收作用", "basis": "T/SHRH 064-2024《化妆品成分经皮渗透测试 人体在体拉曼光谱法》", "method": { "subjectCount": 1, "testSite": "面部皮肤", "testZones": 3, "zoneArea": "1×1 cm²", "pointsPerZone": 5, "parallelTests": 3, "dose": "2 mg/cm²", "instrument": "LabRAM Soleil 超高分辨显微共聚焦拉曼光谱仪" }, "productRamanPeaksCmMinus1": [ 458, 570, 736, 904, 1005, 1223, 1454, 1595, 2967, 3065 ], "timepoints": [ { "time": "0h", "relativePenetrationPercent": 0, "maxObservedDepthMicrometer": 0 }, { "time": "2h", "relativePenetrationPercent": 4.58, "maxObservedDepthMicrometer": 60 }, { "time": "4h", "relativePenetrationPercent": 8.21, "maxObservedDepthMicrometer": 100 } ], "websiteSummary": "报告显示，NLU多效水润次抛精华液（水光小白瓶）的产品特征信号在 2h 与 4h 观察点出现随时间和深度变化的分布记录，其中 4h 相对透皮率记录为 8.21%，最大观察深度记录为 100 μm。" } } }, { "id": "nlu-firming-ampoule", "fullName": "NLU紧致焕肤次抛精华液", "nickname": "线雕小黑瓶", "brandOwner": "递萃生物", "reports": { "efficacy": { "reportType": "人体功效测试", "sourceFile": "人体功效报告-NLU紧致焕肤次抛精华液.pdf", "summarySourceFile": "功效摘要 -NLU紧致焕肤次抛精华液.doc", "institution": "挪亚检测认证集团有限公司", "institutionAddress": "上海市徐汇区吴中路 39 号新概念大厦八层", "testPeriod": { "startDate": "2025-08-18", "endDate": "2025-09-29", "durationDays": 28 }, "claimedFunctionsInReport": [ "保湿", "修护", "舒缓", "紧致", "抗皱", "温和无刺激", "敏感肌适用" ], "subjects": { "count": 33, "ageRange": "30-49", "skinType": "敏感性肌肤受试者", "inclusionSummary": "乳酸刺痛评分阳性、角质层含水量偏低、经皮水分流失基线大于 15g/h/m²，并伴随皮肤松弛、眼下皱纹、粗糙暗沉、泛红或粉刺丘疹等观察条件。" }, "instrumentResults": [ { "metric": "角质层含水量", "endpoint": "corneumMoisture", "direction": "increase", "unit": "%", "day14Change": 26.32, "day28Change": 47.37, "significantDay14": true, "significantDay28": true }, { "metric": "经皮水分流失 TEWL", "endpoint": "tewl", "direction": "decrease", "unit": "%", "day14Change": -13.33, "day28Change": -25.33, "significantDay14": true, "significantDay28": true }, { "metric": "皮肤光泽度", "endpoint": "gloss", "direction": "increase", "unit": "%", "day14Change": 17.41, "day28Change": 29.59, "significantDay14": true, "significantDay28": true }, { "metric": "皮肤弹性 R2", "endpoint": "elasticityR2", "direction": "increase", "unit": "%", "day14Change": 13.59, "day28Change": 17.86, "significantDay14": true, "significantDay28": true }, { "metric": "皮肤紧致度参数 R0", "endpoint": "firmnessR0", "direction": "decrease", "unit": "%", "day14Change": -15.98, "day28Change": -13.92, "significantDay14": true, "significantDay28": true }, { "metric": "皮肤平滑度 SEsm", "endpoint": "smoothnessSEsm", "direction": "decrease", "unit": "%", "day14Change": -4.5, "day28Change": -9.44, "significantDay14": false, "significantDay28": true }, { "metric": "皮肤粗糙度 SEr", "endpoint": "roughnessSEr", "direction": "sourceReportedIncrease", "unit": "%", "day14Change": 26.24, "day28Change": 43.37, "significantDay14": true, "significantDay28": true, "note": "按功效摘要原始方向记录。" }, { "metric": "皱纹面积占比", "endpoint": "wrinkleAreaRatio", "direction": "decrease", "unit": "%", "day14Change": -13.11, "day28Change": -12.3, "significantDay14": true, "significantDay28": true }, { "metric": "眼下皱纹评分", "endpoint": "underEyeWrinkleScore", "direction": "decrease", "unit": "%", "day14Change": -14.29, "day28Change": -21.43, "significantDay14": true, "significantDay28": true } ], "consumerSelfEvaluation": { "unit": "%", "day14": { "水润度改善": 100, "保湿效果": 100, "有助于改善皮肤刺激状态": 100, "舒缓效果": 100, "有助于修护肌肤": 96.97, "肌肤光滑细腻": 100, "改善肌肤粗糙": 100, "有助于减少粉刺发生": 100, "改善肌肤弹性": 100, "紧致效果": 96.97, "改善干纹细纹": 96.97, "抗皱效果": 90.91, "整体认可": 100, "温和无刺激": 100, "适合敏感肌": 100, "未出现不良反应": 100 }, "day28": { "水润度改善": 100, "保湿效果": 100, "有助于改善皮肤刺激状态": 100, "舒缓效果": 100, "有助于修护肌肤": 100, "肌肤光滑细腻": 100, "改善肌肤粗糙": 100, "改善肌肤弹性": 100, "紧致效果": 100, "改善干纹细纹": 96.97, "抗皱效果": 100, "整体认可": 100, "温和无刺激": 100, "适合敏感肌": 100, "未出现不良反应": 100 } }, "adverseReaction": { "subjectsWithAdverseReaction": 0, "totalSubjects": 33, "summary": "33 名受试者在测试期间未出现不良反应。" }, "sourceConclusion": "在测试条件下，D14 和 D28 的检测结果支持产品保湿、修护、舒缓、紧致、抗皱功效评价；33 名受试者未出现不良反应，支持温和无刺激和敏感肌适用评价。" }, "raman": { "reportType": "人体在体拉曼光谱检测", "sourceFile": "拉曼透皮报告-NLU紧致焕肤次抛精华液.pdf", "reportNumber": "NMD2511-0424-01", "sampleNumber": "NMD2511-0424_001", "client": "苏州递萃生物科技有限公司", "institution": "挪亚检验认证集团有限公司", "reportDate": "2025-12-23", "receivedDate": "2025-11-19", "testPeriod": { "startDate": "2025-11-25", "endDate": "2025-12-05" }, "testItem": "透皮吸收作用", "basis": "T/SHRH 064-2024《化妆品成分经皮渗透测试 人体在体拉曼光谱法》", "method": { "subjectCount": 1, "testSite": "面部皮肤", "testZones": 3, "zoneArea": "1×1 cm²", "pointsPerZone": 5, "parallelTests": 3, "dose": "2 mg/cm²", "instrument": "LabRAM Soleil 超高分辨显微共聚焦拉曼光谱仪" }, "productRamanPeaksCmMinus1": [ 847, 1065, 1285, 1461, 1619, 2903, 3225, 3426 ], "timepoints": [ { "time": "0h", "relativePenetrationPercent": 0, "maxObservedDepthMicrometer": 0 }, { "time": "2h", "relativePenetrationPercent": 3.25, "maxObservedDepthMicrometer": 30 }, { "time": "4h", "relativePenetrationPercent": 7.67, "maxObservedDepthMicrometer": 110 } ], "websiteSummary": "报告显示，NLU紧致焕肤次抛精华液（线雕小黑瓶）的产品特征信号在 2h 与 4h 观察点出现随时间和深度变化的分布记录，其中 4h 相对透皮率记录为 7.67%，最大观察深度记录为 110 μm。" } } } ], "websiteUse": { "dataUrl": "https://www.dicuibio.com/assets/data/nlu-detection-reports.json", "primaryPages": [ "https://www.dicuibio.com/raman-evidence.html", "https://www.dicuibio.com/sensitive-skin-testing.html", "https://www.dicuibio.com/products/shuiguang-xiaobaiping.html", "https://www.dicuibio.com/products/xiandiao-xiaoheiping.html" ] } }